| 凌霞,刘晓英,刘蔚,王林波,张玫,彭兴盛.毛细管黏度计法测定微晶纤维素聚合度测量不确定度的评估[J].中国药品标准,2018,19(2):103-107 |
| 毛细管黏度计法测定微晶纤维素聚合度测量不确定度的评估 |
| Evaluation of polymerization degree uncertainty of microcrystalline cellulose determined by capillary viscometry |
| 投稿时间：2017-11-15 修订日期：2018-04-12 |
| DOI： |
| 中文关键词: 毛细管黏度计法 微晶纤维素 聚合度 不确定度 |
| 英文关键词: capillary viscometry microcrystalline cellulose polymerization degree uncertainty |
| 基金项目: |
|
| 摘要点击次数: 811 |
| 全文下载次数: 0 |
| 中文摘要: |
| 目的：对毛细管黏度计法测定微晶纤维素聚合度的测量不确定度进行评估。方法：用进口注册标准的方法建立数学模型,再根据JJF1059.1-2012《测量不确定度的评定与表示》对测量结果的各不确定度来源进行分析和评估。结果：使用黏度计法测量MCC聚合度的不确定度主要来自于特性黏度的测定及重复性。其结果可以表示为224.0±0.6(k = 2)。结论：毛细管黏度计法测定聚合度的测量不确定度的结果是相对较小的,但通过优化特性黏度的测量方式可进一步减小该不确定度的值。 |
| 英文摘要: |
| Objective：To evaluate the uncertainty of polymerization degree of microcrystalline cellulose determined by capillary viscometry. Methods: With establishment of the mathematical model, the main sources of the uncertainty resulted from the determination process were calculated and discussed by the method of JJF1059.1-2012 Evaluation and expression of uncertainty in measurement. Results: The major uncertainty sources were from measurement of intrinsic viscosity and the test repeatability. The results could be expressed as 224.0 ± 0.6 (k = 2). Conclusion: The uncertainty of polymerization degree determined by capillary viscometry can be reduced by optimization of the intrinsic viscometry measurement. |
|
查看/发表评论 下载PDF阅读器 |
| 关闭 |