文章摘要
丁晴,孙鹏飞,李龙囡,夏蕴.中药材及饮片中三种二氧化硫残留量测定方法的比较[J].中国药品标准,2017,18(6):423-427
中药材及饮片中三种二氧化硫残留量测定方法的比较
Comparison of three methods for the determination of sulfur dioxide residues in Chinese medicinal materials and prepared pieces
投稿时间:2017-07-03  修订日期:2017-12-08
DOI:
中文关键词: 二氧化硫  酸碱滴定  气相色谱  离子色谱
英文关键词: sulfur dioxide  acid-base titration  gas chromatography  ion chromatography
基金项目:
作者单位E-mail
丁晴 无锡市药品安全检验检测中心 619370528@qq.com 
孙鹏飞 江南大学药学院  
李龙囡 无锡市药品安全检验检测中心  
夏蕴 南京中医药大学翰林学院  
摘要点击次数: 180
全文下载次数: 185
中文摘要:
      目的 采用酸碱滴定法、气相色谱法、离子色谱法分别测定中药材或饮片中二氧化硫的残留量,比较分析三种检测方法的适用性。方法 采用三种检测方法对19批中药材及饮片中二氧化硫残留量进行测定,选取20种中药材及饮片进行三种方法的空白加标回收试验,并对结果进行比较分析。结果 酸碱滴定法操作简单、成本低。气相色谱法样品测定速度较快,但测定结果偏低、专属性较差。离子色谱法灵敏度高、准确度、精密度好。结论 建议气相色谱法用于粗筛二氧化硫残留量较高的样品,酸碱滴定法作为常规测定方法,离子色谱法作为仲裁方法。
英文摘要:
      Objective The residue of sulfur dioxide in Chinese medicinal herbs and crude drugs were determined by acid-base titration, gas chromatography and ion chromatography. The applicability of the three methods was compared and analyzed. Methods Three methods were used to determine the content of sulfur dioxide in the 19 batches of Chinese herbal medicines and prepared slices, and the recoveries of the 20 kinds of Chinese herbal medicines and the prepared slices were compared. The results are compared and analyzed. Results The method of acid-base titration has the advantages of simple operation and low cost. The method of gas chromatography is rapid, but the result is low and the specificity is poor. Ion chromatography has high sensitivity, accuracy and good precision. Conclusion It is suggested that GC can be used for tentative detection of the high sulfur dioxide sample, the method of acid-base titration can be used as the conventional method, IC can be used as an arbitration method.
  查看/发表评论  下载PDF阅读器
关闭